化合物简介
A highly selective and potent cyclooxygenase-2 inhibitor which has been shown to induce apoptosis in gastric cells via down-regulation of Akt and then release of cytochrome c. Its anti-inflammatory effects allows for potential use in therapy for inflammatory allergic diseases.
基本信息
中文名称
SC-58236
英文名称
4-[5-(4-chlorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
中文别名
英文别名
4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide SC-58236、Tracazolate hydrochloride、4-[5-(4-chorophenyl)-3-(trifluoromethyl)-1H-pyrazole-1-yl]benzenesulfonamide、HMS3262A06、4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-yl)benzenesulfonamide、4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide、SC236
CAS号
170569-86-5
分子式
C16H11ClF3N3O2S
分子量
401.791
精确质量
401.021
PSA
86.36
LOGP
5.64
编号系统
MDL号
MFCD00941297
安全信息
海关编码
2935009090
