化合物简介
Falcarindiol was isolated as an algicidal principle against the harmful red tide dinoflagellate, Heterocapsa circularisquama, from Notopterygii Rhizoma through bioassay-guided separation.To determine the ambiguous absolute structure of this active principle, all three stereoisomers as well as falcarindiol were synthesized. As a result of intensive analytical of their physicochemical properties, the configuration of Falcarinfiol was revealed to be 3R,8S. (3S,8S)- and (3S,8R)-isomers were found to exhibit more potent algicidal activity than (3R,8S)-Falcarindiol isolated from Notopterygii Rhizoma.
基本信息
中文名称
镰叶芹二醇
英文名称
(+)-(3R,8S)-falcarindiol
中文别名
发卡二醇
英文别名
Falcarindiol、1,9-HEPTADECADIENE-4,6-DIYNE-3,8-DIOL,(3R,8S,9Z)-、(3R,8S)-Falcarindiol
CAS号
225110-25-8
分子式
C17H24O2
分子量
260.371
精确质量
260.178
PSA
40.46
LOGP
2.8177
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