化合物简介
Pracinostat is a potent and orally active histone deacetylase (HDAC) inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. The selectivity of Pracinostat for tumor tissues makes it a promising therapeutic candidate for use in patients with advanced solid malignancies.
基本信息
中文名称
Pracinostat
英文名称
(E)-3-[2-butyl-1-[2-(diethylamino)ethyl]benzimidazol-5-yl]-N-hydroxyprop-2-enamide
中文别名
英文别名
Pracinostat (SB939)、SB939、SB939,Pracinostat、Pracinostat、SB-939,SB939
CAS号
929016-96-6
分子式
C20H30N4O2
分子量
358.478
精确质量
358.237
PSA
70.39
LOGP
3.6302
