化合物简介
KL001 is a small molecule that specifically interacts with cryptochrome (CRY). KL001 prevented ubiquitin-dependent degrdation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes making it a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes.
基本信息
中文名称
KL001
英文名称
KL001
中文别名
英文别名
CAS号
309928-48-1
分子式
C21H22N2O4S
分子量
398.475
精确质量
398.13
PSA
84.06
LOGP
4.291
编号系统
MDL号
MFCD02086647
