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10-脱乙酰基巴卡丁 III
CAS号:32981-86-5
英文名:10-deacetylbaccatin III
分子式:C29H36O10
分子量:544.59
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合成路线
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7-O-(三乙基硅烷基)-10-去乙酰基浆果赤霉素III
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10-脱乙酰基巴卡丁 III
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10-脱乙酰基巴卡丁 III
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7-O-chloroacetylbaccatin III
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10-脱乙酰基巴卡丁 III
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紫杉醇
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10-脱乙酰基巴卡丁 III
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7-表-10-脱乙酰基紫杉醇
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10-脱乙酰基巴卡丁 III
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(3aS,5S,7aS,10aS,11S,12R,12aS)-6,9,9,11,13,13-hexamethyl-2-oxo-5-((triisopropylsilyl)oxy)-5,7a,10a,11,12,12a-hexahydro-4H-3a,7-methanocyclodeca[1,2-d:5,6-d']bis([1,3]dioxole)-12-carbaldehyde
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10-脱乙酰基巴卡丁 III
187960-85-6
2-((3aS,5S,8S,9S,10S,11R,11aS)-8,9-dihydroxy-6,10,12,12-tetramethyl-2-oxo-5-((triisopropylsilyl)oxy)-5,8,9,10,11,11a-hexahydro-4H-3a,7-methanocyclodeca[d][1,3]dioxol-11-yl)acetaldehyde
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10-脱乙酰基巴卡丁 III
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2-((3aS,5S,8S,9S,10S,11R,11aS)-8-hydroxy-6,10,12,12-tetramethyl-2-oxo-9-((triethylsilyl)oxy)-5-((triisopropylsilyl)oxy)-5,8,9,10,11,11a-hexahydro-4H-3a,7-methanocyclodeca[d][1,3]dioxol-11-yl)acetaldehyde
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10-脱乙酰基巴卡丁 III
187960-87-8
2-((1S,5S,6S,7S,8S,12S)-7,11,14,14-Tetramethyl-3,9-dioxo-8-triethylsilanyloxy-12-triisopropylsilanyloxy-2,4-dioxa-tricyclo[8.3.1.01,5]tetradec-10-en-6-yl)-propenal
32981-86-5
10-脱乙酰基巴卡丁 III
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上游原料
10-dehydro-10-deacetylbaccatin III (V)
巴卡丁 III
2-((3aS,5S,8S,9S,10S,11R,11aS)-8,9-dihydroxy-6,10,12,12-tetramethyl-2-oxo-5-((triisopropylsilyl)oxy)-5,8,9,10,11,11a-hexahydro-4H-3a,7-methanocyclodeca[d][1,3]dioxol-11-yl)acetaldehyde
7-O-chloroacetylbaccatin III
2-((1S,5S,6S,7S,8S,12S)-7,11,14,14-Tetramethyl-3,9-dioxo-8-triethylsilanyloxy-12-triisopropylsilanyloxy-2,4-dioxa-tricyclo[8.3.1.01,5]tetradec-10-en-6-yl)-propenal
10-deacetyl-7,10-bis-trichloroacetylbaccatine III
三尖杉宁碱
(3aS,5S,9S,10S,11S,11aS)-11-((R)-3-((benzyloxy)methoxy)hexa-1,5-dien-2-yl)-6,10,12,12-tetramethyl-9-((triethylsilyl)oxy)-5-((triisopropylsilyl)oxy)-4,5,9,10,11,11a-hexahydro-8H-3a,7-methanocyclodeca[d][1,3]dioxole-2,8-dione
苯基锂
7-表-10-去乙酰基浆果赤霉素III
(3aS,5S,7aS,10aS,11S,12R,12aS)-6,9,9,11,13,13-hexamethyl-2-oxo-5-((triisopropylsilyl)oxy)-5,7a,10a,11,12,12a-hexahydro-4H-3a,7-methanocyclodeca[1,2-d:5,6-d']bis([1,3]dioxole)-12-carbaldehyde
巴卡亭III
7-表-10-脱乙酰基紫杉醇
甲醇
(3aS,5S,9S,10S,11S,11aS)-11-((R)-3-((benzyloxy)methoxy)hexa-1,5-dien-2-yl)-9-hydroxy-6,10,12,12-tetramethyl-5-((triisopropylsilyl)oxy)-4,5,9,10,11,11a-hexahydro-8H-3a,7-methanocyclodeca[d][1,3]dioxole-2,8-dione
7-α-glucosyloxyacetyl paclitaxel
(1S,5S,6S,7S,8S,12S)-6-((R)-2-Hydroxy-1-methylene-pent-4-enyl)-7,11,14,14-tetramethyl-8-triethylsilanyloxy-12-triisopropylsilanyloxy-2,4-dioxa-tricyclo[8.3.1.01,5]tetradec-10-ene-3,9-dione
2’-TES-taxol
2-((3aS,5S,8S,9S,10S,11R,11aS)-8-hydroxy-6,10,12,12-tetramethyl-2-oxo-9-((triethylsilyl)oxy)-5-((triisopropylsilyl)oxy)-5,8,9,10,11,11a-hexahydro-4H-3a,7-methanocyclodeca[d][1,3]dioxol-11-yl)acetaldehyde
紫杉醇
7-O-(三乙基硅烷基)-10-去乙酰基浆果赤霉素III
10-O-去乙酰基-7-O-beta-D-吡喃木糖基浆果赤霉素 III
下游产品
10-乙酰多西他赛
4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β-hydroxy-7β,10β-dimethoxy-9-oxo-11-taxene-13α-yl (2R,4S,5R)-3-tert-butoxycarbonyl-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylate
3'-N-debenzoyltaxol
卡巴他赛
7β,10β-二甲氧基多西紫杉醇
巴卡丁 III
(2α,3α,4α,5β,7α,10β,13α)-4,10-bis(acetyloxy)-1,13-dihydroxy-9-oxo-5,20-epoxy-7,19-cyclotax-11-en-2-yl benzoate
7,10-di-O-chloroacetyl-10-deacetylbaccatin III
13-{[(3-t-叔丁氧羰基)-2,2-二甲基-4S-苯基-1,3-恶唑烷-5R-基]甲酰基}-7-O-(2,2,2-三氯乙基)氧基]羰基)浆果赤霉素III
7,10-二[O-(三乙基硅烷基)]-10-去乙酰基浆果赤霉素III
7-O-(2,2,2-三氯乙氧基羰基)浆果赤霉素 III
Larotaxel
紫杉醇
7-O-(三乙基硅烷基)-10-去乙酰基浆果赤霉素III
N-去-t-叔丁氧羰基-10-去乙酰基-7,10-O-二{[(2,2,2-三氯乙基)氧基]羰基}多西他赛
7,10-二(2,2,2-三氯乙氧羰基)-10-脱乙酰基巴卡丁 III
7,10,13-tri(2,2,2-tricholoroethyloxycarbonyl)-10-deacetyl baccatin III