[1(Z,Z),6(2alpha,3beta,4beta)]-(4R,5R)-4,5-二羟基-N2-(1-氧代-9,12-十八碳二烯基)-L-鸟氨酰-L-苏氨酰-反式-4-羟基-L-脯氨酰-(S)-4-羟基-4-(4-羟基苯基)-L-苏氨酰-L-苏氨酰-3-羟基-4-甲基-L-脯氨酸环 (6→1)-肽

Echinocandin B, a lipopeptide, is a naturally occurring cyclic hexapeptide with a linoleoyl side chain. It belongs to a class of antifungal agents called echinocandins, which inhibits the synthesis of glucan, a major component of the fungal cell wall, via noncompetitive inhibition of a crucial enzyme, β-(1,3)-D-glucan synthase. Echinocandin B is a fermentation product of Aspergillus nidulans and the closely related species, A. rugulosus; discovered in 1974 in A. nidulans var. echinulatus strain A 32204 in Germany, it was the first of the echinocandin class of antifungals.