化合物简介
Pixantrone is an antineoplastic drug belonging to group of antitumor antibiotics. Pixantrone is an anlogue of Mitoxantrone and is just as potent in the treatment of multiple sclerosis with fewer toxic effects on cardiac tissue. Studies suggest that Pixantrone significantly reduces amyloid beta (A beta(1-42)) neurotoxicity, a mechanism implicated in Alzheimer's disease.
基本信息
中文名称
匹杉群马来酸盐
英文名称
Benz[g]isoquinoline-5,10-dione, 6,9-bis[(2-aminoethyl)amino]-, (2Z)-2-butenedioate (1_2)
中文别名
马来到匹杉琼
英文别名
Pixantrone maleate、Bbr 2778
CAS号
144675-97-8
分子式
C21H23N5O6
分子量
441.437
精确质量
441.165
PSA
197.73
LOGP
1.8566
编号系统
MDL号
MFCD28142718
物化性质
沸点
650ºC at 760mmHg
闪点
346.9ºC
蒸汽压
8.89E-17mmHg at 25°C