化合物简介
Intermedine is an unsaturated monoester pyrrolizidine alkaloid that is extracted from the seeds of Amsinckia intermedia, a tarweed that causes enzootic hepatic cirrhosis in horses and hard liver disease in cattle. Intermedine is also a diastereomer of Lycopsamine, a pyrrolizidine alkaloid that is found in honey and in comfrey (a topical anti-inflammatory agent used to treat patients with arthritis and gout).
基本信息
中文名称
促黑激素
英文名称
intermedine
中文别名
英文别名
[(7R,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2S)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate、Intermedina [INN-Spanish]、Butanoic acid,2,3-dihydroxy-2-(1-methylethyl)-,((1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester,(2S,3R)、9-(+)-Trachelanthylretronecine、lycopsamine、Intermedine、[(1r,7ar)-1-hydroxy-2,3,5,7a-tetrahydro-1h-pyrrolizin-7-yl]methyl(2s,3r)-2,3-dihydroxy-2-(propan-2-yl)butanoate、Intermedinum [INN-Latin]、Intermedina、Intermedinum
CAS号
10285-06-0
分子式
C15H25NO5
分子量
299.363
精确质量
299.173
PSA
90.23
LOGP
-0.3894
物化性质
密度
1.26g/cm3
沸点
463.3ºC at 760mmHg
闪点
234ºC
折射率
1.567
蒸汽压
1.57E-10mmHg at 25°C
安全信息
危险品运输编码
UN 1544
危险类别
6.1(b)
包装等级
III
