化合物简介
Zonampanel (INN, code name YM872) is a quinoxalinedione derivative drug and competitive antagonist of the AMPA receptor which was being investigated by Yamanouchi/Astellas Pharma as a neuroprotective drug for the treatment of ischemic stroke but never completed clinical trials. In clinical trials, zonampanel produced severe side effects including hallucinations, agitation, and catatonia in patients, resulting in early termination of the trials.
基本信息
中文名称
唑南帕奈
英文名称
2-(7-imidazol-1-yl-6-nitro-2,3-dioxo-4H-quinoxalin-1-yl)acetic acid
中文别名
英文别名
Zonampanel、Ym 872
CAS号
210245-80-0
分子式
C13H9N5O6
分子量
331.24
精确质量
331.055
PSA
155.8
LOGP
0.3915
编号系统
UNII
9X33544ILS
