化合物简介
URB597 (KDS-4103) is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH). FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery where it activates cannabinoid receptors. URB597 has been found to elevate anandamide levels and have activity against neuropathic pain in a mouse model.
基本信息
中文名称
3’-氨基甲酰-[1,1’-联苯]-3-基 环己基氨基甲酸酯
英文名称
3'-Carbamoyl-[1,1'-biphenyl]-3-yl cyclohexylcarbamate
中文别名
3\'-胺甲酰基联苯-3-基环己基氨基甲酸甲酯、3\'-胺甲酰基联苯-3-基环己基氨基甲酸酯、东凌草素、N-环己基氨基甲酸 3\'-(氨基甲酰基)[1,1\'-联苯]-3-基酯
英文别名
[3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate
CAS号
546141-08-6
分子式
C20H22N2O3
分子量
338.4
精确质量
338.163
PSA
81.42
LOGP
4.9648
编号系统
MDL号
MFCD05863934
安全信息
安全说明
S22; S24/25; S60; S61
危险类别码
R50/53
危险品运输编码
UN 3077 9/PG 3
海关编码
2924299090
危险标志
GHS07, GHS09
危险性防范说明
P273; P305 + P351 + P338; P501
信号词
Warning
危险性描述
H319; H410