化合物简介
Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride), also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class. It is considered to be obsolete, and is now seldom used. It is marketed in Europe, including in Poland, Spain, and the United Kingdom. Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide, but is less toxic in comparison, despite still being a toxic drug. As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed. Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin.
基本信息
中文名称
苯丁酰脲
英文名称
2-PHENYLBUTYRYLUREA
中文别名
乙苯乙酰脲、1-((乙基)苯乙酰)脲、Beta刴ethoxynaph-talene
英文别名
Phenuride、Lircapyl、PHENETURIDE、S 46、Benuride、ETHYLPHENACEMIDE、PBU
CAS号
90-49-3
分子式
C11H14N2O2
分子量
206.241
精确质量
206.106
PSA
72.19
LOGP
2.4663
编号系统
UNII
878CEJ4HGX
物化性质
密度
1.15g/cm3
折射率
1.547
安全信息
危险品运输编码
UN 3249
危险类别
6.1(b)
包装等级
III