化合物简介
Amcinonide (trade name Cyclocort) is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis. Amcinonide can also be classified as a multi-functional small molecule corticosteroid, which has been approved by the FDA and is currently marketed as an ointment, lotion, or cream. It acts as both a transcription factor for responses to glucocorticoids and modulator for other transcription factors while also regulating phospholipase A2 activity.
基本信息
中文名称
安西奈德
英文名称
amcinonide
中文别名
英文别名
Amcinonid、Penticort、Amicla、cyclocort、Visderm、Amcinopol、Amciderm、AMCINONIDE
CAS号
51022-69-6
分子式
C28H35FO7
分子量
502.572
精确质量
502.237
PSA
99.13
LOGP
3.5238
编号系统
UNII
423W026MA9
物化性质
外观与性状
白色至淡黄色粉末
密度
1.33 g/cm3
沸点
635.9ºC at 760 mmHg
闪点
338.4ºC
折射率
1.586