化合物简介
Liquiritigenin is a flavanone that was isolated from Glycyrrhiza uralensis, and is found in a variety of plants, including Glycyrrhiza glabra (licorice). It is an estrogenic compound which acts as a selective agonist of the ERβ subtype of the estrogen receptor (ER), though it is also reported to act as an ERα partial agonist at sufficient concentrations. It also has a choleretic effect.
基本信息
中文名称
甘草素
英文名称
liquiritigenin
中文别名
甘草醇、4\',7-二羟基黄烷酮、4\',7-二羟基黄酮
英文别名
(2S)-7-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one、4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (S)-、Liquiritigenin
CAS号
578-86-9
分子式
C15H12O4
分子量
256.253
精确质量
256.074
PSA
66.76
LOGP
2.8043
编号系统
UNII
T194LKP9W6
物化性质
密度
1.386g/cm3
沸点
529.5ºC at 760mmHg
熔点
206-208ºC
闪点
206.9ºC
折射率
1.661
