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截短侧耳素

截短侧耳素

CAS号：125-65-5

英文名：Pleuromutilin

分子式

C22H34O5

熔点

170-171ºC

密度

1.15 g/cm3 (20ºC)

分子量

378.502

沸点

483ºC

溶解度

信号词

危险品标志

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化合物简介

Pleuromutilin and its derivatives are antibacterial drugs that inhibit protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.

基本信息

中文名称

截短侧耳素

英文名称

Pleuromutilin

中文别名

Mutilin 14-乙醇酸酯

英文别名

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-hydroxyacetate、Drosophilin B、Mutilin 14-glycolate、Pleuromulin、Valnemulin impurity E

CAS号

125-65-5

分子式

C22H34O5

分子量

378.502

精确质量

378.241

PSA

83.83

LOGP

2.8852

编号系统

EINECS号

204-747-5

物化性质

外观与性状

结晶固体

密度

1.15 g/cm3 (20ºC)

沸点

483ºC

熔点

170-171ºC

折射率

1.537

蒸汽压

2.38E-11mmHg at 25°C

安全信息

海关编码

2918199090

合成路线

(3S,3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-3-ol

(3S,3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-3-ol

截短侧耳素

截短侧耳素

上游原料

共找到5个上游原料 >

(3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyloctahydro-4,9a-propanocyclopenta[8]annulen-3(3aH)-one

(3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyloctahydro-4,9a-propanocyclopenta[8]annulen-3(3aH)-one

5,8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-octahydro-3a,9-propano-cyclopentacycloocten-1-one

5,8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-octahydro-3a,9-propano-cyclopentacycloocten-1-one

(3R,3aS,4S,5S,7R,8R,9S,9aR,12S)-3-(benzyloxy)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulene

(3R,3aS,4S,5S,7R,8R,9S,9aR,12S)-3-(benzyloxy)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulene

Acetic acid 2-methanesulfonyloxy-2-oxo-ethyl ester

Acetic acid 2-methanesulfonyloxy-2-oxo-ethyl ester

(3S,3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-3-ol

(3S,3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-3-ol

上游原料

(3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyloctahydro-4,9a-propanocyclopenta[8]annulen-3(3aH)-one 5,8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-octahydro-3a,9-propano-cyclopentacycloocten-1-one (3R,3aS,4S,5S,7R,8R,9S,9aR,12S)-3-(benzyloxy)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulene Acetic acid 2-methanesulfonyloxy-2-oxo-ethyl ester (3S,3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-3-ol