化合物简介
Diloxanide (INN) is a luminal amebicide used in the treatment of amebiasis. It is formulated as the furoate ester diloxanide furoate. It is considered the luminal agent of choice for mild intestinal amebiasis or asymptomatic cyst carriers. It can also be added to metronidazole (active drug in luminal and extraintestinal amebiasis) in acute amebic dysentery as well as hepatic abscess(In hepatic abscess it is for the control of cysts in the lumen which may cause relapse). The drug was discovered by The Boots Company Plc in 1956 and introduced as Furamide. The Furamide brand is now owned by Abbott Laboratories. It is not available in the United States. In India it is available as Amicline by Franco-Indian.
基本信息
中文名称
糠酸二氯尼特
英文名称
[4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate
中文别名
4-(N-甲基-2,2-二氯乙酰氨基)苯基 2-糠酸酯、糠酯酰胺
英文别名
Amebiazol、Miforon、Diclofurazol、Furamide (amebicide)、Diloxanid furoate、Entamide furoate、Furentomin、Entamide 2-furoate、Histomibal、DILOXANIDE FUROATE、2-Furancarboxylic acid, 4-[(dichloroacetyl)methylamino]phenyl ester
CAS号
3736-81-0
分子式
C14H11Cl2NO4
分子量
328.147
精确质量
327.007
PSA
59.75
LOGP
3.2653
编号系统
UNII
YP4N72IW34
安全信息
安全说明
S36
危险类别码
R22