化合物简介
Thapsigargin is non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA). Structurally, thapsigargin is classified as a sesquiterpene lactone, and is extracted from a plant, Thapsia garganica. It is a tumor promoter in mammalian cells.
基本信息
中文名称
毒胡萝卜素
英文名称
thapsigargin
中文别名
英文别名
Thallium mononitrate、thallous nitrate TlNO3,orthorhombic、THALLIUM NITRATE、THALLOUS NITRATE、thallous、Pamoic acid disodium salt、Thapsigargin,(3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yloctanoate、Thapsigargin、sesquiterpene lactone、sesquiterpene lactone tetraester、rcrawastenumberu217
CAS号
67526-95-8
分子式
C34H50O12
分子量
650.754
精确质量
650.33
PSA
171.96
LOGP
3.9279
编号系统
UNII
Z96BQ26RZD
物化性质
储存条件
−20°C
安全信息
安全说明
S26; S36/37/39
WGK Germany
3
危险类别码
R36/37/38; R42
危险品运输编码
UN 2811 6.1/PG 2
危险品标志
Xn; T
危险性描述
H315; H319; H334; H335
信号词
Danger
危险标志
GHS07, GHS08
危险性防范说明
P261; P305 + P351 + P338; P342 + P311