化合物简介
Caspofungin (INN) (brand name Cancidas worldwide) is a lipopeptide antifungal drug from Merck & Co., Inc. discovered by James Balkovec, Regina Black and Frances A. Bouffard. It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration. Caspofungin is administered intravenously.
基本信息
中文名称
醋酸卡泊芬净
英文名称
caspofungin acetate
中文别名
英文别名
CASPOFUNGIN、Cancidas、Mk0991、L-743,872、Caspofungin Diacetate、Caspofungin diacetate
CAS号
179463-17-3
分子式
C52H88N10O15
分子量
1093.31
精确质量
1092.64
PSA
412.03
LOGP
0.0615
编号系统
UNII
VUW370O5QE
物化性质
沸点
1408.1ºC at 760 mmHg
蒸汽压
0mmHg at 25°C
安全信息
海关编码
2933990090
生产方法及用途
用途
抗肿瘤药。