化合物简介
Azimilide Dihydrochloride is an oral type III potassium channel blocker agent that blocks both the rapid activating component and the slow activating component of the delayed rectifier potassium current. Both preclinical and clinical studies have demonstrated the efficacy of azimilide and its safety in the treatment of supraventricular and ventricular tachyarrhythmia. Azimilide also is being studied in a worldwide multicenter trial for prevention of sudden cardiac death in patients after myocardial infarction.
基本信息
中文名称
盐酸阿齐利特
英文名称
1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione,dihydrochloride
中文别名
英文别名
azmilide、Azimilide hydrochloride、Stedicor、Azimilide HCl、Azimilide dihydrochloride
CAS号
149888-94-8
分子式
C23H30Cl3N5O3
分子量
530.875
精确质量
529.141
PSA
72.6
LOGP
4.5813
物化性质
密度
1.32g/cm3
沸点
594.9ºC at 760mmHg
闪点
313.6ºC