化合物简介
Suloctidil was a sulfer-containing aminoalcohol that was brought to market in the early 1970s as a vasodilator by Continental Pharma, a Belgian company.:118–121; Continental was bought by Monsanto in 1984, primarily on the promise of sales of suloctidil, which was approved in Europe at the time, but not in the US. However, in 1985 Monsanto halted development and withdrew the drug worldwide following reports of liver toxicity.:251
基本信息
中文名称
舒洛地尔
英文名称
(1S,2R)-2-(octylamino)-1-(4-propan-2-ylsulfanylphenyl)propan-1-ol
中文别名
英文别名
GNF-Pf-1859、Suloctidil、(1S,2R)-1-[4-(methylethylthio)phenyl]-2-(octylamino)propan-1-ol、Suloctidil (USAN/INN)、CP-556S
CAS号
54767-75-8
分子式
C20H35NOS
分子量
337.563
精确质量
337.244
PSA
57.56
LOGP
5.95
编号系统
UNII
XV1N1XY17K
物化性质
密度
0.99g/cm3
沸点
467.3ºC at 760 mmHg
闪点
236.4ºC
折射率
1.528
储存条件
2-8ºC
蒸汽压
1.56E-09mmHg at 25°C
安全信息
RTECS号
DO8910000
危险类别码
R22
WGK Germany
3
危险品标志
Xn
