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瑞舒伐他汀内酯

瑞舒伐他汀内酯

CAS号：503610-43-3

英文名：Rosuvastatin Lactone

分子式

C22H26FN3O5S

熔点

密度

分子量

463.522

沸点

溶解度

信号词

危险品标志

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化合物简介

Intermediate in the production of Rosuvastatin derivatives.

基本信息

中文名称

瑞舒伐他汀内酯

英文名称

Rosuvastatin Lactone

中文别名

罗舒伐他汀内酯

英文别名

ROSUVASTATIN-5S-LACTONE、(3R,5R)-ROSUVASTATIN LACTONE、Rosuvastatin lactone、RosuvastatinLactone

CAS号

503610-43-3

分子式

C22H26FN3O5S

分子量

463.522

精确质量

463.158

PSA

118.07

LOGP

3.9624

编号系统

UNII

FL37W41F3T

合成路线

瑞舒伐他汀

瑞舒伐他汀

瑞舒伐他汀内酯

瑞舒伐他汀内酯

上游原料

共找到21个上游原料 >

瑞舒伐他汀甲酯

瑞舒伐他汀甲酯

ethyl 4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidine-5-carboxylate

ethyl 4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidine-5-carboxylate

N-[5-chloromethyl-4-(4-fluorophenyl)-6-isopropyl-pyrimidin-2-yl]-N-methyl-methanesulfonamide

N-[5-chloromethyl-4-(4-fluorophenyl)-6-isopropyl-pyrimidin-2-yl]-N-methyl-methanesulfonamide

4-(4-氟苯基)-6-异丙基-2-[(N-甲基-N-甲磺酰)氨基]嘧啶-5-甲醇

4-(4-氟苯基)-6-异丙基-2-[(N-甲基-N-甲磺酰)氨基]嘧啶-5-甲醇

(4R-Cis)-6-羟甲基-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯

(4R-Cis)-6-羟甲基-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯

瑞舒伐他汀

瑞舒伐他汀

上游原料

瑞舒伐他汀甲酯 ethyl 4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidine-5-carboxylate N-[5-chloromethyl-4-(4-fluorophenyl)-6-isopropyl-pyrimidin-2-yl]-N-methyl-methanesulfonamide 4-(4-氟苯基)-6-异丙基-2-[(N-甲基-N-甲磺酰)氨基]嘧啶-5-甲醇 (4R-Cis)-6-羟甲基-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯瑞舒伐他汀 2-[(4R,6S)-6-hydroxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]-N-methoxy-N-methyl-acetamide (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid methylammonium salt (4R,6S)-4-(tert-butyldimethylsilyloxy)-6-(dihydroxymethyl)tetrahydro-2H-pyran-2-one N-[5-(联苯-膦酰基甲基)-4-(4-氟-苯基)-6-异丙基-嘧啶-2-基]-N-甲基-甲烷磺胺 2-[(4R,6S)-6-methanesulfonyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]-N-methoxy-N-methyl-acetamide 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-yl)acetic acid 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl )-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate methyl ester E-(6-{2-[2-(N-methyl-N-methanesulfonylamino)-4-(4-fluorophenyl)-6-isopropyl-pyrimidin-5-yl]vinyl}-[(4R,6S)-2,2-dimethyl-[1,3]dioxan-4-yl])-N-methoxy-N-methyl-acetamide (6-{(E)-2-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]vinyl}-(4R,6S)-2,2-dimethyl[1,3]dioxan-4-yl)-acetic acid ethyl ester [(4R,6S)-6-methanesulfonyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]-acetic acid 2-[(4R,6S)-2,2-dimethyl-6-(1-phenyl-1H-tetrazole-5-sulfonylmethyl)-[1,3]dioxan-4-yl]-N-methoxy-N-methyl-acetamide 2-[(4R,6S)-6-formyl-2,2-dimethyl-[1,3]dioxan-4-yl]-N-methoxy-N-methyl-acetamide 5-(溴甲基)-4-(4-氟苯基)-6-异丙基-2-[甲基(甲磺酰)氨基]嘧啶瑞舒伐他汀叔丁酯 N-[5-[[(benzothiazol-2-yl)thio]methyl]-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methyl methanesulfonamide