化合物简介
Quizartinib (AC220) is a small molecule receptor tyrosine kinase inhibitor that is currently under development by Ambit Biosciences for the treatment of acute myeloid leukaemia. Its molecular target is FLT3, also known as CD135 which is a proto-oncogene.
基本信息
中文名称
N-(5-叔丁基-异噁唑-3-基)-N-{4-[7-(2-吗啉-4-基乙氧基)咪唑并[2,1-b][1,3]苯并噻唑-2-基]苯基}脲
英文名称
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
中文别名
托舍多特
英文别名
AC220,Quizartinib、Quizartinib、AC-220,AC220、AC-220
CAS号
950769-58-1
分子式
C29H32N6O4S
分子量
560.667
精确质量
560.221
PSA
134.4
LOGP
5.9404
编号系统
MDL号
MFCD18074524
