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1-[1-(1-甲基环辛基)-4-哌啶基]-2-(3R)-3-哌啶基-1H-苯并咪唑 三盐酸盐

1-[1-(1-甲基环辛基)-4-哌啶基]-2-(3R)-3-哌啶基-1H-苯并咪唑 三盐酸盐

CAS号:1108147-88-1
英文名:MCOPPB (hydrochloride)
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化合物简介
A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.
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