化合物简介
3-Chloro-5-fluorophenol is a useful synthetic intermediate. It was used to prepare substituted amides as antagonists and/or inverse agonists of cannabinoid-1 receptor. It was also used to synthesize substituted N-(arylmethyl)aryloxy arylcarboxamide and heteroarylcarboxamide antagonists for the PGE2 receptor EP4 for the treatment of pain, inflammation, osteoarthritis, and rheumatoid arthritis.
基本信息
中文名称
3-氯-5-氟苯酚
英文名称
3-CHLORO-5-FLUOROPHENOL
中文别名
英文别名
3-chloranyl-5-fluoranyl-phenol、3-chloro-5-fluoro-phenol
CAS号
202982-70-5
分子式
C6H4ClFO
分子量
146.547
精确质量
145.993
PSA
20.23
LOGP
2.1847
编号系统
MDL号
MFCD00042212
物化性质
密度
1.408g/cm3
沸点
206ºC at 760mmHg
闪点
78.4ºC
折射率
1.537
蒸汽压
0.17mmHg at 25°C
安全信息
安全说明
S26-S36/37/39
危险类别码
R20/21/22
海关编码
2908199090
危险品标志
Xi