化合物简介
2-Methyl-N-[3-(trifluoromethyl)phenyl]propanamide is used as a reagent to synthesize Flutamide, an oral nonsteroidal antiandrogen that is hepatotoxic and commonly used to treat patients with prostate cancer.
基本信息
中文名称
3-(异丁酰氨基)-1-三氟甲基苯
英文名称
3'-Trifluoromethylisobutyranilide
中文别名
2-甲基-N-(3-三氟甲基苯基)丙酰胺
英文别名
PropanaMide,2-Methyl-N-[3-(trifluoroMethyl)phenyl]、3-(Isobutyryladmino)-1-(trifluoro-methyl)benzene、isobutyric acid-(3-trifluoromethyl-anilide)、2-methyl-N-[3-(trifluoromethyl)phenyl]propionamide、2-METHYL-N-(3-TRIFLUOROMETHYLPHENYL) PROPANAMIDE、m-trifluoromethyl isobutyranilide、Ethanone,1-(2-hydroxy-4,5-dimethylphenyl)、3-Isobutyrylamino-1-trifluormethyl-benzol、3-trifluoromethylisobutyranilide、Isobuttersaeure-(3-trifluormethyl-anilid)、2-Methyl-N-(a,a,a-trifluoro-M-tolyl)propionaMide
CAS号
1939-27-1
分子式
C11H12F3NO
分子量
231.214
精确质量
231.087
PSA
29.1
LOGP
3.3729
物化性质
外观与性状
白色结晶
密度
1.22 g/cm3
沸点
313.5ºC at 760 mmHg
熔点
100-101ºC
折射率
1.489
稳定性
Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
蒸汽压
0.000493mmHg at 25°C
安全信息
安全说明
S22; S36; S61
危险类别码
R48/22
危险品标志
Xn; N
