化合物简介
HU-243 (AM-4056) is a synthetic cannabinoid drug that is a single enantiomer of the hydrogenated derivative of the commonly used reference agonist HU-210. It is a potent agonist at both the CB1 and CB2 receptors, with a binding affinity of 0.041nM at the CB1 receptor, making it marginally more potent than HU-210, which had an affinity of 0.061nM in the same assay.
基本信息
中文名称
[6aR-(6aalpha,8beta,9alpha,10abeta)]-3-(1,1-二甲基庚基)-6a,7,8,9,10,10a-六氢-9-氚代-1-羟基-6,6-二甲基-6H-二苯并[b,d]吡喃-8-氚代-9-甲醇
英文名称
(6aR,8S,9S,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-8,9-ditritio-7,8,10,10a-tetrahydro-6aH-benzo[c]chromen-1-ol
中文别名
英文别名
3-Dimethylheptyl-11-hydroxyhexahydrocannabinol、6H-Dibenzo(b,d)pyran-8-t-9-methanol,3-(1,1-dimethylheptyl)-6a,7,8,9,10,10a-hexahydro-9-t-1-hydroxy-6,6-diemthyl-,(6aR-(6aalpha,8beta,9alpha,10abeta))、(3H)HU 243
CAS号
140835-18-3
分子式
C25H38O3T2
分子量
392.6
精确质量
392.314
PSA
49.69
LOGP
6.3034
物化性质
沸点
472.2ºC at 760 mmHg
闪点
239.4ºC
蒸汽压
1.02E-09mmHg at 25°C
