百科

2’-C-甲基尿苷

CAS号：31448-54-1

英文名：1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione

分子式

C10H14N2O6

熔点

110-112ºC

密度

1.572

分子量

258.228

沸点

溶解度

信号词

危险品标志

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化合物简介

A 2’-C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity.

基本信息

中文名称

2’-C-甲基尿苷

英文名称

1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione

中文别名

2\'-C-甲基尿苷

英文别名

BCX-4018、2\'-C-methyl uridine、Uridine,2\'-C-methyl、2\'-methyluridine

CAS号

31448-54-1

分子式

C10H14N2O6

分子量

258.228

精确质量

258.085

PSA

124.78

LOGP

-2.4618

物化性质

密度

1.572

熔点

110-112ºC

合成路线

共找到2条合成路线 >

23643-36-9

2'-C-甲基尿苷 2',3',5'-三苯甲酸酯

上游原料

1,3-di-O-acetyl-2-C-methyl-5-O-p-methylbenzoyl-β-D-ribofuranose

114952-95-3

1,3-di-O-acetyl-2-O-benzyl-2-C-methyl-5-O-p-methylbenzoyl-β-D-ribofuranose

157037-56-4

ALPHA-D-赤式戊呋喃糖-2-酮 1,3,5-三苯甲酸酯

110808-85-0

3-O-benzyl-1,2-O-isopropylidene-3-C-methyl-6-O-methylbenzoyl-α-D-allofuranose

22224-41-5

1,3,5-三苯甲酰基-D-呋喃核糖

15397-15-6

1,2,3,5-四苯甲酰氧基-2-C-甲基-beta-D-呋喃核糖

下游产品

上游原料

1,3-di-O-acetyl-2-C-methyl-5-O-p-methylbenzoyl-β-D-ribofuranose 1,3-di-O-acetyl-2-O-benzyl-2-C-methyl-5-O-p-methylbenzoyl-β-D-ribofuranose ALPHA-D-赤式戊呋喃糖-2-酮 1,3,5-三苯甲酸酯 3-O-benzyl-1,2-O-isopropylidene-3-C-methyl-6-O-methylbenzoyl-α-D-allofuranose 1,3,5-三苯甲酰基-D-呋喃核糖 1,2,3,5-四苯甲酰氧基-2-C-甲基-beta-D-呋喃核糖 3-O-Benzyl-3-C-methyl-1,2-O-isopropylidene-α-D-allofuranose 2'-C-methyl-2'-O-(tetrahydropyran-2-yl)uridine 2'-C-methyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-hydroxymethyleneuridine 1-((6aR,8R,9aS)-2,2,4,4-tetraisopropyl-9-methylenetetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-pyrimidine-2,4(1H,3H)-dione 2'-C-methyl-2',3'-O-isopropylidenuridine (2R,3R,3aS,9aR)-3-hydroxy-2-(hydroxymethyl)-3a-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-p-toluenesulfonylmethyleneuridine 1,2,3-tri-O-acetyl-2-C-methyl-5-O-p-methylbenzoyl-β-D-ribofuranose 2'-C-甲基尿苷 2',3',5'-三苯甲酸酯 2',3'-di-O-benzoyl-5'-O-(4-methoxytrityl)-2'-C-methyluridine 1-(2,3-di-O-acetyl-2-C-methyl-5-O-p-methylbenzoyl-β-D-ribofuranosyl)uracil ((2R,3R,3aS,9aR)-3-(benzoyloxy)-3a-methyl-6-oxo-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-2-yl)methyl benzoate 尿嘧啶

下游产品

2’-C-甲基胞嘧啶核苷 2'-甲基-2'-脱氧胞苷