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醋酸乌利司他中间体
CAS号：159811-51-5
英文名：(8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
分子式：C28H35NO3
分子量：433.582
上游原料
3-(ethylenedioxy)estra-5,10-epoxy-9(11)-ene-17-one
(5alpha,11beta)-11-[4-(二甲基氨基)苯基]-5,17-二羟基-19-去甲基雄甾-9-烯-3,20-二酮双(1,2-乙二醇)环缩醛
3-ethylenedioxy-17β-cyano-17α-chloromethyl(dimethyl)silyloxyestra-5(10),9(11)-diene
3-(ethylenedioxy)estra-5α,10α-epoxy-17α-ethynyl-17β-hydroxy-9(11)-ene
4-溴-N,N-二甲基苯胺
醋酸优力司特中间体
3,3-(ethylenedioxy)-17α-ethynyl-17β-hydroxyestra-5(10),9(11)-diene
(5alpha,10alpha)-5,10-环氧-17-羟基-19-去甲雄甾-9(11)-烯-3,20-二酮环-3,20-双(1,2-乙缩醛)
(5alpha,11beta,17alpha)-11-[4-(二甲基氨基)苯基]-5,17-二羟基-19-去甲孕-9-烯-20-炔-3-酮环1,2-乙二基缩醛
3-缩酮
