化合物简介
N-2-Naphthalenyl-glycine 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide is a glycine hydrazide that has recently been shown to block CFTR channels. However, its effects on cardiomyocytes are unknown. Studies have demonstrated that GlyH-101 blocks cardiac I Cl.PKA channels in a similar fashion to that reported for recombinant CFTR.
基本信息
中文名称
GlyH 101
英文名称
N'-[(3,5-dibromo-4-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]-2-(naphthalen-2-ylamino)acetohydrazide
中文别名
英文别名
GlyH-101、N\'-[(Z)-(3,5-dibromo-4-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]-2-(naphthalen-2-ylamino)acetohydrazide、(Naphthalen-2-ylamino)-acetic acid (3,5-dibromo-2,4,-dihydroxy-benzylidene)-hydrazide
CAS号
328541-79-3
分子式
C19H15Br2N3O3
分子量
493.149
精确质量
490.948
PSA
93.95
LOGP
5.0866
