化合物简介
Lomitapide (INN, marketed as Juxtapid in the US and as Lojuxta in the EU) is a drug used as a lipid-lowering agent for the treatment of familial hypercholesterolemia, developed by Aegerion Pharmaceuticals. It has been tested in clinical trials as single treatment and in combinations with atorvastatin, ezetimibe and fenofibrate.
基本信息
中文名称
N-(2,2,2-三氟乙基)-9-(4-[4-[4’-(三氟甲基)[1,1’-联苯]-2-甲酰氨基]哌啶-1-基]丁基)-9H-芴-9-甲酰胺
英文名称
lomitapide
中文别名
英文别名
UNII-82KUB0583F、N-(2,2,2-trifluoroethyl)-9-[4-[4-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]piperidin-1-yl]butyl]fluorene-9-carboxamide、Lomitapide、AEGR 733、Juxtapid
CAS号
182431-12-5
分子式
C39H37F6N3O2
分子量
693.72
精确质量
693.279
PSA
68.42
LOGP
9.7351
编号系统
UNII
82KUB0583F
