化合物简介
A-836,339 is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist. It is selective for CB2, with Ki values of 0.64nM at CB2 vs 270nM at the psychoactive CB1 receptor, but while it exhibits selective analgesic, anti-inflammatory and anti-hyperalgesic effects at low doses, its high efficacy at both targets results in typical cannabis-like effects appearing at higher doses, despite its low binding affinity for CB1. In 2012 A-836,339 was detected via X-ray crystallography in a \"dubious product\" sold in Japan, though the product was described as a white powder, not herbal incense, it was suggested to be for human consumption.
基本信息
中文名称
N-[3-(2-methoxyethyl)-4,5-dimethyl-1,3-thiazol-2-ylidene]-2,2,3,3-tetramethylcyclopropane-1-carboxamide
英文名称
N-[3-(2-methoxyethyl)-4,5-dimethyl-1,3-thiazol-2-ylidene]-2,2,3,3-tetramethylcyclopropane-1-carboxamide
中文别名
英文别名
UNII-Z6Y1J258EG、A-836,339
CAS号
959746-77-1
分子式
C16H26N2O2S
分子量
310.455
精确质量
310.171
PSA
71.83
LOGP
2.9223
编号系统
UNII
Z6Y1J258EG