化合物简介
5-Hydroxyuracil is an oxidized form of cytosine that is produced by the oxidative deamination of cytosines by reactive oxygen species. It does not distort the DNA molecule and is bypassed by replicative DNA polymerases. It can miscode for adenine and is potentially mutagenic.
基本信息
中文名称
异巴比妥酸
英文名称
5-hydroxyuracil
中文别名
2,4,5-三叔丁基苯酚、2,4,5-三羟基嘧啶
英文别名
5-Hydroxyuracil、2,4,5-Trihydroxypyrimidine、Fluorouracil impurity B、5-hydroxyisouracil、2,4,6-ThihydroxypyriMidine、2,4,5(3H)-Pyrimidinetrione, dihydro-、Isobarbitursaeure、ISOBARBITURIC ACID、Isobarbituric Acid、TRIFLUOROACETIC ACID REAGENTPLUS、2,4,5-Trihydroxypyrimidine,5-Hydroxyuracil,Isobarbituric acid
CAS号
496-76-4
分子式
C4H4N2O3
分子量
128.086
精确质量
128.022
PSA
85.95
LOGP
-1.2312
编号系统
UNII
438WJI1S49
物化性质
密度
1.605g/cm3
沸点
534.5ºC at 760mmHg
熔点
300ºC
闪点
277ºC
折射率
1.492
安全信息
安全说明
S26-S37/39
危险类别码
R36/37/38
危险品标志
Xi
