化合物简介
Favipiravir, also known as T-705 or Avigan, is an experimental antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses. Like some other experimental antiviral drugs (T-1105 and T-1106), it is a pyrazinecarboxamide derivative. Favipiravir is active against influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated.
基本信息
中文名称
6-氟-3-羟基吡嗪-2-甲酰胺
英文名称
5-fluoro-2-oxo-1H-pyrazine-3-carboxamide
中文别名
6-氟-3,4-二氢-3-氧代-吡嗪羧酰胺、2-羟基-3-甲酰胺基-5-氟吡嗪
英文别名
6-FLUORO-3-HYDROXYPYRAZINE-2-CARBOXAMIDE、6-fluoro-3-hydroxypyrazine-2-carboxaMide、2-Pyrazinecarboxamide,6-fluoro-3-hydroxy、UNII-EW5GL2X7E0、6-fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide、6-fluoro-3-hydroxy-2-pyrazinecarboxamide、T-705、Favipiravir
CAS号
259793-96-9
分子式
C5H4FN3O2
分子量
157.103
精确质量
157.029
PSA
88.84
LOGP
-0.2918
物化性质
密度
1.78 g/cm3
沸点
552.6ºC at 760 mmHg
安全信息
海关编码
2934999090
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