化合物简介
It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.
基本信息
中文名称
N,N-二(2-氯乙基)(4,4,5,5-2H4)-1,3,2-氧氮杂磷杂环己烷-2-胺2-氧化物
英文名称
N,N-bis(2-chloroethyl)-4,4,5,5-tetradeuterio-2-oxo-1,3,2λ<sup>5</sup>-oxazaphosphinan-2-amine
中文别名
英文别名
Cytoxan-d4、Endoxan-d4、Cyclostin-d4、Cyclophosphamide-d4、Genoxal-d4、Mitoxan-d4、Hexadrin-d4、Cycloblastin-d4
CAS号
173547-45-0
分子式
C7H11Cl2D4N2O2P
分子量
265.111
精确质量
264.05
PSA
51.38
LOGP
2.2128
物化性质
熔点
41-45 °C
蒸汽压
0mmHg at 25°C
