化合物简介
A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
基本信息
中文名称
O-羟基阿伐他汀内酯
英文名称
2-Hydroxy Atorvastatin Lactone
中文别名
2-羟基阿托伐他汀内酯
英文别名
5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N-(2-hydroxyphenyl)-4-phenyl-2-propan-2-ylpyrrole-3-carboxamide
CAS号
163217-74-1
分子式
C33H33FN2O5
分子量
556.624
精确质量
556.237
PSA
100.79
LOGP
6.5721
编号系统
MDL号
MFCD00936960
物化性质
熔点
110-112ºC