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(3aR,4S,6R,6aS)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇

CAS号：155899-66-4

英文名：(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

分子式

C8H15NO3

熔点

85-88ºC

密度

1.17

分子量

173.21

沸点

288ºC

溶解度

信号词

危险品标志

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化合物简介

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol was used to preapare AZD6140 as an orally active reversible P2Y12 receptor antagonist for prevention of thrombosis.

基本信息

中文名称

(3aR,4S,6R,6aS)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇

英文名称

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

中文别名

替卡格雷中间体1

英文别名

CAS号

155899-66-4

分子式

C8H15NO3

分子量

173.21

精确质量

173.105

PSA

64.71

LOGP

0.2987

物化性质

密度

1.17

沸点

288ºC

熔点

85-88ºC

闪点

128ºC

合成路线

共找到3条合成路线 >

155855-51-9

tetrahydro-2,2-dimethyl-6-phenylmethyl-(3aS,4S,7R,7aS)-4,7-methano-4H-1,3-dioxolo[4,5-d][1,2]oxazine

155899-66-4

(3aR,4S,6R,6aS)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇

上游原料

共找到26个上游原料 >

4099-85-8

甲基-2,3-O-异亚丙基-beta-D-呋喃核糖苷

(1R,2R,3S,4R)-4-benzyloxyamino-2,3-O-isopropylidene-1,2,3-cyclopentane triol

542-92-7

环戊二烯

190517-38-5

(1S,4R,5S,6R)-2,3-oxazabicyclo[2.2.1]heptane-5,6-dioxy-isopropylidene

下游产品

共找到3个下游商品 >

274693-53-7

N-[(3aS,4R,6S,6aR)-四氢-6-羟基-2,2-二甲基-4H-环戊烯并-1,3-二氧戊环-4-基]氨基甲酸苄酯

274693-27-5

替格瑞洛

274693-55-9

2-[[(3aR,4S,6R,6aS)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-基]氧基]乙醇

上游原料

甲基-2,3-O-异亚丙基-beta-D-呋喃核糖苷 Cis-3,5-二乙酰氧基-1-环戊烯顺式-4-环戊烯-1,3-二醇 (1R,2R,3S,4R)-4-benzyloxyamino-2,3-O-isopropylidene-1,2,3-cyclopentane triol 环戊二烯 (1S,4R,5S,6R)-2,3-oxazabicyclo[2.2.1]heptane-5,6-dioxy-isopropylidene 6-噁双环[3.1.0]-3-己烯 (4R)-(+)-羟基-2-环戊酮 (1S,4R)-顺式-4-乙酰氧基-2-环戊烯-1-醇 (3aS,4S,6aR)-4-(iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole (4R,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolane-4-carbaldehyde N-(((4S,5R)-2,2-dimethyl-5-vinyl-1 ,3-dioxolan-4-yl)methylene)-1-phenylmethanamine oxide tert-butyl ((R)-1-((1S,4R)-2-oxa-3-azabicyclo[2.2.1]hept-5-en-3-yl)-1-oxopropan-2-yl)carbamate (3aR,4R,6S,6aS)-6-(iodomethyl)-4-methoxy-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole (1S,2R,3S,4R)-4-O-benzylhydroxylamino-2,3-O-isopropylidene-1,2,3-cyclopentanetriol (1S,2R,3S,4R)-4-(N-phthalimidyl)cyclopentane-1,2,3-triol (1S,2R,3S,4R)-4-(N-phthalimidyl)-2,3-O-isopropylidenecyclopentane-1,2,3-triol 1-O-methyl-2,3-O-isopropylidene-5-O-(methanesulfonyl)-β-D-ribofuranoside 糠醇 (3aS,4S,6aR)-4-(bromomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole 1-甲氧基-2,3-O-异亚丙基-5-O-对甲苯磺酰基-beta-D-呋喃核糖苷 D-吡喃核糖 (+)-(1S,4R)-4-phthalimidyl-2-cyclopenten-1-ol tetrahydro-2,2-dimethyl-6-phenylmethyl-(3aS,4S,7R,7aS)-4,7-methano-4H-1,3-dioxolo[4,5-d][1,2]oxazine (3aR,4S,6R,6aS)-6-(benzylamino)-2,2-dimethyltetrahydro-3ah-cyclopenta-[d][1,3]-dioxol-4-ol

下游产品

N-[(3aS,4R,6S,6aR)-四氢-6-羟基-2,2-二甲基-4H-环戊烯并-1,3-二氧戊环-4-基]氨基甲酸苄酯替格瑞洛 2-[[(3aR,4S,6R,6aS)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-基]氧基]乙醇