化合物简介
Epiberberine is a natural bioactive alkaloid, an isomer of Berberine, an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.
基本信息
中文名称
表小檗碱
英文名称
Epiberberine
中文别名
英文别名
GNF-Pf-2355、HMS2229E04、pseudo-Epiberberin、Benz(a)-1,3-benzodioxolo(4,5-g)quinolizinium,11,12-dihydro-8,9-dimethoxy、Epiberberin、epiberberinium、8,9-dimethoxy-11,12-dihydro-[1,3]dioxolo[4,5-h]isoquino[2,1-b]isoquinolinylium
CAS号
6873-09-2
分子式
C20H18NO4+
分子量
336.361
精确质量
336.124
PSA
40.8
LOGP
3.0963
物化性质
熔点
260ºC
