化合物简介
AR-42 is a broad spectrum deacetylase inhibitor of both histone and non-histone proteins, which has demonstrated greater potency and activity in solid tumors and hematological malignancies. AR-42 is known utilized as a novel, oral cancer therapy currently in early clinical development.
基本信息
中文名称
(S)-(+)-N-羟基-4-(3-甲基-2-苯基丁酰氨基)苯甲酰胺
英文名称
N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide
中文别名
英文别名
AR-42,HDAC-42,OSU-HDAC42、AR 42、HDAC-42、OSU-HDAC42
CAS号
935881-37-1
分子式
C18H20N2O3
分子量
312.363
精确质量
312.147
PSA
78.43
LOGP
3.6478
编号系统
UNII
E0GG29V0AQ
安全信息
海关编码
2924299090
