化合物简介
Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography. It has a peak spectral absorption at about 800nm. These infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography. ICG binds tightly to plasma proteins and becomes confined to the vascular system. ICG has a half-life of 150 to 180 seconds and is removed from circulation exclusively by the liver to bile juice.
基本信息
中文名称
吲哚菁绿
英文名称
indocyanine green
中文别名
吲哚氰绿、CY3染料、心脏绿、靛氰绿、福氏绿
英文别名
IR-125,laser grade、Cardiogreen,Foxgreen,IC Green、Cardio-green、Indocyanine Green、Indocyanine green、Foxgreen,IC Green,Indocyanine green、Sodium 2-(7-(3,3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
CAS号
3599-32-4
分子式
C43H47N2NaO6S2
分子量
774.963
精确质量
774.277
PSA
137.41
LOGP
10.5557
编号系统
UNII
IX6J1063HV
物化性质
外观与性状
绿色至绿色-棕色粉末
沸点
157ºC
熔点
235 °C
水溶解性
slightly soluble
稳定性
Stable under normal temperatures and pressures.
储存条件
库房低温通风干燥
安全信息
RTECS号
DE3150000
安全说明
S26-S36-S37/39
危险类别码
R36/37/38
WGK Germany
3
危险品标志
Xi
生产方法及用途
生产方法
由l,1,2-三甲基苯基(e)吲哚为原料制得。
用途
为颜色指示剂,用于心脏输入量和肝功能测定。对本品过敏及有过敏既往史者、有碘过敏既往史者禁用。