化合物简介
Peptide T is an HIV entry inhibitor discovered in 1986 by researchers at the National Institutes of Health in the United States. Peptide T, and its modified analog Dala1-peptide T-amide (DAPTA), a drug in clinical trials, is a short peptide derived from the HIV envelope protein gp120 which blocks binding and infection of viral strains which use the CCR5 receptor to infect cells.
基本信息
中文名称
L-丙氨酰-L-丝氨酰-L-苏氨酰-L-苏氨酰-L-苏氨酰-L-天冬氨酰胺酰-L-酪氨酰-L-苏氨酸
英文名称
peptide T
中文别名
英文别名
Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr
CAS号
106362-32-7
分子式
C35H55N9O16
分子量
857.862
精确质量
857.377
PSA
431.49
LOGP
-3.7121
编号系统
UNII
05DYM3ZS1X
物化性质
蒸汽压
0mmHg at 25°C