化合物简介
Pleconaril (Picovir) is an antiviral drug that was being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in patients exposed to picornavirus respiratory infections. Pleconaril, administered either orally or intranasally, is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus. It has shown useful activity against the dangerous strain enterovirus D68.
基本信息
中文名称
普可那利
英文名称
3-[3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
中文别名
英文别名
Pleconaril、Picovir
CAS号
153168-05-9
分子式
C18H18F3N3O3
分子量
381.349
精确质量
381.13
PSA
74.18
LOGP
4.6802
编号系统
MDL号
MFCD00923611
物化性质
密度
1.271
沸点
481.2ºC at 760mmHg
闪点
244.8ºC
折射率
1.509
蒸汽压
5.94E-09mmHg at 25°C