化合物简介
Diphenylpyraline (DPP; sold as Allergen, Arbid, Belfene, Diafen, Hispril, Histyn, Lergobine, Lyssipol, Mepiben, Neargal) is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class. It is marketed in Europe for the treatment of allergies. DPP has also been found to act as a dopamine reuptake inhibitor and produces hyperactivity in rodents. It has been shown to be useful in the treatment of Parkinsonism.
基本信息
中文名称
双苯拉林
英文名称
diphenylpyraline
中文别名
4-(二苯基甲氧基)-1-甲基哌啶
英文别名
4-Benzhydryloxy-1-methyl-piperidin、Lergobine、Dayfen、4-Diphenylmethoxy-1-methyl-piperidin、Allergen、Belfene、4-benzhydryloxy-1-methylpiperidine、4-benzhydryloxy-1-methyl-piperidine、4-(diphenylmethoxy)-1-methylpiperidine、Histyn、Mepiben、Hispril、N-methyl-4-(diphenylmethoxy)piperidine、Lyssipoll、Neargal
CAS号
147-20-6
分子式
C19H23NO
分子量
281.392
精确质量
281.178
PSA
12.47
LOGP
3.8247
编号系统
EINECS号
205-686-7
物化性质
密度
1.08 g/cm3
沸点
378.7ºC at 760 mmHg
闪点
111.6ºC
折射率
1.587
蒸汽压
6.18E-06mmHg at 25°C
安全信息
危险品运输编码
UN 3249
海关编码
2933399090
危险类别
6.1(b)
包装等级
III
