化合物简介
(16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.
基本信息
中文名称
(16beta)-17,21-二羟基-16-甲基孕甾-1,4,9(11)-三烯-3,20-二酮
英文名称
(8S,10S,13S,14S,16S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one
中文别名
英文别名
EINECS 236-830-7、(16|A)-17,21-dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
CAS号
13504-15-9
分子式
C22H28O4
分子量
356.455
精确质量
356.199
PSA
74.6
LOGP
2.7529
编号系统
EINECS号
236-830-7
物化性质
密度
1.24g/cm3
沸点
548.3ºC at 760mmHg
闪点
299.4ºC
折射率
1.603
蒸汽压
2.63E-14mmHg at 25°C
合成路线