化合物简介
Carbetocin (INN, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors. It is manufactured by Ferring Pharmaceuticals and is available in Canada and the United Kingdom and many other countries throughout the world, but notably not in the United States.
基本信息
中文名称
卡贝缩宫素
英文名称
carbetocin
中文别名
醋酸卡贝缩宫素、卡比托辛
英文别名
Carbetocin Acetate、(BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT、CARBETOCIN TRIFLUOROACETATE SALT、Depotocin、CARBETOCIN、M.W. 988.17 C45H69N11O12S、Carbansin、DeaMino-2-O-Methyltyrosine-1-carbaoxytocin
CAS号
37025-55-1
分子式
C45H69N11O12S
分子量
988.161
精确质量
987.485
PSA
387.81
LOGP
1.9637
编号系统
EINECS号
253-312-6
物化性质
密度
1.218 g/cm3
沸点
1477.9ºCat 760 mmHg
闪点
847.6ºC
折射率
1.541
储存条件
-15ºC