化合物简介
Hycanthone is the schistosomicide approved by the FDA in 1975. It is a metabolite of lucanthone. Hycanthone interferes with parasite nerve function, resulting in paralysis and death. This agent also intercalates into DNA and inhibits RNA synthesis in vitro and shows potential antineoplastic activity.
基本信息
中文名称
海恩酮
英文名称
hycanthone
中文别名
1-[(2-[二乙基氨基]乙基)氨基]-4-[羟基甲基]-9h-噻吨酮
英文别名
lucanthonemetabolite、1-(2-diethylaminoethylamino)-4-methylol-thioxanthen-9-one、1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE、1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one、ETRENOL、hycanthon、Etrenol(mesylate)、1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-9h-thioxanthen-9-on、HYCANTHONE、Win 249-33
CAS号
3105-97-3
分子式
C20H24N2O2S
分子量
356.482
精确质量
356.156
PSA
80.81
LOGP
3.7337
编号系统
MDL号
MFCD00083383
物化性质
密度
1.25g/cm3
沸点
570.5ºC at 760mmHg
熔点
approx 143ºC
闪点
298.9ºC
折射率
1.658
储存条件
-20ºC
安全信息
危险类别码
R45; R46; R20/21/22
海关编码
2932999099
危险品标志
T
