化合物简介
Intepirdine (INN; developmental codes SB-742457, RVT-101) is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials; however, GSK chose not to continue development and sold the rights to Axovant Sciences in December 2014.
基本信息
中文名称
3-苯磺酰基-8-(哌嗪-1-基)喹啉
英文名称
3-(benzenesulfonyl)-8-piperazin-1-ylquinoline
中文别名
渥曼青霉素
英文别名
Quinoline,3-(phenylsulfonyl)-8-(1-piperazinyl)、3-(phenylsulfonyl)-8-(piperazin-1-yl)quinoline
CAS号
607742-69-8
分子式
C19H19N3O2S
分子量
353.438
精确质量
353.12
PSA
70.68
LOGP
3.9518
编号系统
UNII
2IOB2M82HY
