化合物简介
Plerixafor (INN and USAN, trade name Mozobil) is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients into the bloodstream. The stem cells are then extracted from the blood and transplanted back to the patient. The drug was developed by AnorMED which was subsequently bought by Genzyme.
基本信息
中文名称
普乐沙福
英文名称
AMD3100 octahydrochloride hydrate
中文别名
AMD 3100辛基盐酸盐、1,1\'-[1,4-亚苯基双(亚甲基)]双[1,4,8,11-四氮杂环十四烷]
英文别名
AMD 3100 octahydrochloride,1,1\'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane)octahydrochloride、Plerixafor 8HCl (AMD3100 8HCl)、1,4,8,11-Tetraazacyclotetradecane (1,1\'-[1,4-phenylenebis(methylene)]bis
CAS号
155148-31-5
分子式
C28H62Cl8N8
分子量
794.469
精确质量
790.261
PSA
78.66
LOGP
8.6804
编号系统
UNII
OD49913540
物化性质
密度
0.962g/cm3
沸点
657.5ºC at 760mmHg
闪点
361.8ºC
储存条件
-20ºC
蒸汽压
2.85E-33mmHg at 25°C
安全信息
安全说明
S22; S24/25
生产方法及用途
用途
普乐沙福治疗骨髓瘤药物。
