化合物简介
Tizanidine (trade names Relentus from Beximco Pharma, Zanaflex, Sirdalud) is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a sleep aid, and as an anticonvulsant. It is also prescribed for some symptoms of fibromyalgia.
基本信息
中文名称
替扎尼定
英文名称
tizanidine
中文别名
5-氯-4-(4,5-二氢-1H-咪唑-2-基)-2,1,3-苯并噻二唑-4-胺
英文别名
Tizanidinum [INN-Latin]、Ternelin、5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine、Sirdalud、5-chloro-N-(imidazolidin-2-ylidene)-2,1,3-benzothiadiazol-4-amine、UNII-6AI06C00GW、Zanaflex(R)、Tizanidina [INN-Spanish]、Tizanidina、[14C]-Tizanidine、5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole、Tizanidinum、Zanaflex
CAS号
51322-75-9
分子式
C9H9Cl2N5S
分子量
290.172
精确质量
288.996
PSA
90.44
LOGP
2.3552
编号系统
EINECS号
610-648-1
物化性质
外观与性状
白色固体
密度
1.82 g/cm3
沸点
391.2ºC at 760 mmHg
熔点
221 - 223ºC
闪点
190.4ºC
稳定性
This material is stable if stored as directed.
储存条件
This product should be stored at room temperature. It should be kept in a tightly closed container.
安全信息
RTECS号
DK9910000
安全说明
S26; S36
WGK Germany
3
危险类别码
R22
海关编码
2934999090
危险品标志
Xn
