化合物简介
Lorglumide (CR-1409) is a drug which inhibits gastrointestinal motility and reduces gastric secretions, acting as a cholecystokinin antagonist, with fairly high selectivity for the CCKA subtype. It has been suggested as a potential treatment for a variety of gastrointestinal problems including stomach ulcers, irritable bowel syndrome, dyspepsia, constipation and pancreatitis, as well as some forms of cancer, but animal and human testing has produced inconsistent results and no clear therapeutic role has been established, although it is widely used in scientific research.
基本信息
中文名称
氯戊米特钠盐
英文名称
LORGLUMIDE
中文别名
氯戊米特、(±)-4-[(3,4-二氯苄基)氨基]-5-(二戊基氨基)-5-氧戊酸钠
英文别名
cr1409、(+/-)-4-[3,4-dichlorobenzoylamino]-5-(dipentylamino)-5-oxopentanoate、4-dichlorobenzoyl)amino)-5-(dipentylamino)-5-oxo-4-(((+-)-pentanoicaci、D,L-4-(3,4-dichloro-benzoyl-amino)-5-(di-n-pentyl-amino)-5-oxo-pentanoic acid、d,l-4-(3,4-dichlorobenzoylamino)-5-(dipentylamino)-5-oxo-pentanoicacid、(R,S-4-[(3,4-dichlorobenzoyl)amino]-5-(dipentylamino)-5-oxopentanoic acid)
CAS号
97964-56-2
分子式
C22H32Cl2N2O4
分子量
459.406
精确质量
458.174
PSA
86.71
LOGP
5.5565
编号系统
UNII
LAD1UQ73BE
物化性质
密度
1.195g/cm3
沸点
621.4ºC at 760mmHg
闪点
329.6ºC
安全信息
RTECS号
SA3680700
WGK Germany
2