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    ChemeGen ChemeGen KDM5A inhibitor 1 纯度:98% CAS:1905481-36-8 (5mg/瓶) C105843 1905481-36-8
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    ¥4140
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    KDM5A inhibitor 1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A inhibitor 1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B).