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ChemeGen ChemeGen (S,R,S)-AHPC hydrochloride 纯度:98% CAS:1448189-80-7 (100mg/瓶) C105921 1448189-80-7
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¥3420
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(S,R,S)-AHPC hydrochloride (MDK7526 hydrochloride) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC hydrochloride can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells.
